High Quality Clarithromycin Powder API CAS 81103-11-9 Raw Material Clarithromycin
Name : Clarithromycin
Shape : White or quasi-white crystalline powder;It is odorless and tastes bitter.Soluble in chloroform, soluble in acetone or ethyl acetate, slightly soluble in methanol or ethanol, insoluble in water
Use for :
A macrolide class of antibiotics, used for the treatment of upper and lower respiratory tract infections, subcutaneous soft tissue infections
This product belongs to 14 - yuan ring macrolide antibiotics.The antimicrobial spectrum was the same as that of erythromycin and roxithromycin, but the antimicrobial activity against gram-positive bacteria such as streptococcus, pneumococcus and staphylococcus was slightly better, and it also had certain antimicrobial activity against induced erythromycin resistant strains.Clarithromycin and its metabolites in vivo have enhanced antibacterial activity against influenza bacillus.The product also has a certain effect on Neisseria gonorrhoeae, Listeria, Campylobacter jejuni, while the effect on Legionella pneumophila, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, etc., is stronger than erythromycin, and the effect is more prominent in the new varieties developed in recent years, the MIC90 is about 0.008 ~ 0.12mg/L.In addition, it had certain activity against Pertospirosis, Mycobacterium avium, Toxoplasma murine, and most of them were better than other varieties.In addition to the anaerobic coccus has a strong antibacterial effect, the effect on the vulnerable bacilli is better than erythromycin, such as the product on staphylococcus aureus, streptococcus pyogenes, influenzae antibiotic after-effect is obviously stronger than erythromycin.This drug is a macrolide antibiotic, and its mechanism is to inhibit the synthesis of protein by blocking the connection of the nuclear protein 50S subunit, and thus produce bacteriostatic effect.This drug has an inhibitory effect on Gram-positive bacteria such as Staphylococcus aureus, Streptococcus, Pneumococcus, and some Gram-negative bacteria such as Haemophilus influenzae, Bacillus pertussis, Diplococcus gonorrhoeae, Legionella pneumophila, and some anaerobic bacteria such as Bacteroides fragilis, Streptococcus digestibility, Propionibacter acnes.In addition to mycoplasma also has an inhibitory effect.The antibacterial activity of this drug is similar to that of Erythromycin in vitro, but stronger than that of Erythromycin in vivo against some bacteria such as Staphylococcus aureus, Streptococcus and Haemophilus influenzae.There was cross resistance to erythromycin
| Name |
CAS |
molecular formula |
Density |
|
| Clarithromycin |
81103-11-9 |
C38H69NO13 |
1.18 |
|
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