| Customization: | Available |
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| CAS: | 146062-45-5 |
| Molecular Formula: | C19h20n2o3s |
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Pioglitazone, a thiazolidinedione anti-diabetic drug, is an insulin sensitizer. Its mechanism of action is related to the presence of insulin. It can reduce insulin resistance in peripheral tissues and liver, increase insulin-dependent glucose processing, and reduce glycogen output . Unlike sulfonylureas, this product is not an insulin secretagogue. Its mechanism of action is highly selective activation of the peroxidase body activated receptor-γPPAR-γ1. The activation of PPAR-γ can regulate the transcription of many insulin-related genes that control glucose and lipid metabolism.
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Foreign name Pioglitazone Chemical formula C19H20N2O3S Molecular weight 356.44 Appearance white to off-white solid Density 1.26 g/cm³ Melting point 183 to 184 ºC Boiling point 575.4 ºC |
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