| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product name | Dinoprost |
| Cas number | 551-11-1 |
| Molecular formula | C20H34O5 |
| Molecular weight | 354.48 |
| Appearance | White to off-white crystalline solid |
| Melting point | 25-35ºC |
| Boiling point | 531ºC at 760 mmHg |
| Relative density | 1.153 g/cm3 |
Indications
Induced abortion in the second trimester of pregnancy (16 weeks to 20 weeks) and expired abortion, fetal death or congenital malformation of the fetus can also be used for induction of labor during term pregnancy and for angiography.
Pharmacokinetics
Absorption after amniocentesis, slowly entering the systemic circulation, the average abortion takes 20h ~ 24h, T1/2 in amniotic fluid is 3h ~ 6h, T1/2 is shorter than 1min in intravenous injection. Degraded in the lungs and liver, metabolites are mainly excreted from the kidneys.
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Item |
Standard |
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Structural data confirmation |
1. H-NMR: The data of structure are identical with reference standard |
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2. HPLC-MS: Ensure the molecular weight of main peak and fragment peak are identical with reference standard |
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3. IR:The data of IR are identical with that of reference standard |
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Purity(HPLC) |
≥99.0% |
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Related impurities |
Specific single impurity |
Meets EP/USP/BP standards |
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Non-specific single impurity |
≤0.10% |
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Total Impurities |
≤0.50% |
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Crystal form |
Meets EP/USP/BP standards |
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Loss on drying |
≤1.0% |
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Water |
≤1.0% |
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Inorganic salt |
≤0.1% |
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Heavy metals |
≤10 ppm |
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Assay |
99.0%~101.0%(According to EP/USP/BP standards) |
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Microbiological Analysis |
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Total plate count |
≤1000cfu/g |
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Yeast and Moulds |
≤100cfu/g |
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E. Coli. |
Absent |
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Salmonella |
Absent |
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S.aureus |
Absent |
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